Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CCR1 | P32246 | 3/20 | 0.55 |
| ▸ | CCR5 | P51681 | 3/20 | 0.55 |
| ▸ | CCR8 | P51685 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913447 | 0.90 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA | |
| SCHEMBL30637256 | 0.90 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA | |
| SCHEMBL2750124 | 0.80 | L3MBTL1 (0.63) | SMN1; SMN2L3MBTL1LMNAALOX15TDP1 | |
| SCHEMBL18769070 | 0.77 | KDM4E (0.65) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA | |
| SCHEMBL2720567 | 0.75 | KDM4E (0.63) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA | |
| SCHEMBL313802 | 0.75 | KDM4E (0.63) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA | |
| SCHEMBL14732968 | 0.75 | KDM4E (0.63) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA | |
| SCHEMBL20863011 | 0.75 | KDM4E (0.63) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA | |
| SCHEMBL13596181 | 0.75 | KDM4E (0.63) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA | |
| SCHEMBL2085837 | 0.75 | KDM4E (0.63) | KDM4ESMN1; SMN2L3MBTL1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035917-A1 | SYNTHESIS OF FLUORINATED NUCLEOTIDES | MERCK SHARP & DOHME CORP. (US) | 2022-02-17 | — | — | WO | disclosed |