SCHEMBL24255100

SCHEMBL24255100

Cc1cc(Nc2c(C)c(C)c(C)c(C)c2C)cc(C)c1C

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 19/20 0.48
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
G6PD P11413 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1155340 0.82 MEN1 (0.48) RAPGEF4MEN1GAAG6PDKMT2A
SCHEMBL17858147 0.80 MAPT (0.46) RAPGEF4GAAL3MBTL1
SCHEMBL26314573 0.74 RAPGEF4 (0.36) RAPGEF4
SCHEMBL29196018 0.73 RAPGEF4 (0.50) RAPGEF4GAAKMT2A
SCHEMBL28561556 0.70 NPSR1 (0.48) RAPGEF4MEN1GAAKMT2AL3MBTL1
SCHEMBL20209999 0.70 RAPGEF4 (0.79) RAPGEF4
SCHEMBL22814186 0.70 RAPGEF4 (0.60) RAPGEF4MEN1GAAG6PDKMT2A
SCHEMBL22814198 0.70 HSD17B10 (0.55) MEN1GAAKMT2AL3MBTL1
SCHEMBL12895790 0.70 MAPT (0.41) MEN1GAAKMT2AL3MBTL1
SCHEMBL3978752 0.69 RAPGEF4 (0.55) RAPGEF4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022034916-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2022-02-17 WO disclosed