SCHEMBL26314573

SCHEMBL26314573

Cc1cc(Nc2c(C)c(C)c(C)c(C)c2C)c(C)c(C)c1C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 8/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29196037 0.87 RAPGEF4 (0.33) RAPGEF4
SCHEMBL22814250 0.80 RAPGEF4 (0.40) RAPGEF4
SCHEMBL28765196 0.75 RAPGEF4 (0.31) RAPGEF4
SCHEMBL24255100 0.74 RAPGEF4 (0.48) RAPGEF4
SCHEMBL4089566 0.74 CYP1A2 (0.32)
SCHEMBL10763176 0.72
SCHEMBL29196013 0.70 RAPGEF4 (0.52) RAPGEF4
SCHEMBL22814197 0.70 RAPGEF4 (0.70) RAPGEF4
SCHEMBL13776396 0.70 RAPGEF4 (0.73) RAPGEF4
SCHEMBL29196018 0.69 RAPGEF4 (0.50) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240237533-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2024-07-11 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR RAPGEF4 4718/4885
US-20240237533-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, C1R, ORC3 RAPGEF4 3204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.