Sugi Predict

Sugi Predict / Compounds / SCHEMBL24256449

SCHEMBL24256449

SCHEMBL24256449

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(N(c4ccc5ccccc5c4)c4ccc5ccccc5c4)c4c3oc3ccccc34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.39
▸ KDM4E B2RXH2 5/20 0.39
▸ POLB P06746 2/20 0.39
▸ MAPT P10636 9/20 0.37
▸ CDC14B O60729 2/20 0.36
▸ CDC14A Q9UNH5 2/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ KMT2A Q03164 5/20 0.35
▸ TSHR P16473 4/20 0.35
▸ LMNA P02545 4/20 0.35
▸ HTT P42858 1/20 0.35
▸ CYP1A2 P05177 3/20 0.34
▸ CYP2C9 P11712 2/20 0.34
▸ CYP2C19 P33261 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ HSD17B10 Q99714 4/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24256430 0.97 ALDH1A1 (0.37) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL25799512 0.97 ALDH1A1 (0.38) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL24256916 0.92 ALDH1A1 (0.36) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL24256089 0.90 MAPT (0.35) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL26313063 0.90 CDC14B (0.34) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL26313044 0.90 ALDH1A1 (0.38) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL26313011 0.89 KDM4E (0.32) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL24256098 0.89 MEN1 (0.36) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL24256897 0.89 ALDH1A1 (0.41) ALDH1A1KDM4EPOLBMAPTCDC14B
SCHEMBL25802795 0.89 ALDH1A1 (0.41) ALDH1A1KDM4EPOLBMAPTCDC14B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230292599-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO.,LTD. (KR) 2023-09-14 — — US disclosed
US-20230292599-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO.,LTD. (KR) 2023-09-14 — — US disclosed
EP-4201930-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-06-28 — — EP disclosed
WO-2022035224-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE 엘티소재주식회사 2022-02-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230292599-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE CRY1, PPOX, ORC3 ALDH1A1 412/4885KDM4E 2416/4885POLB 1189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.