Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24256511 | 0.77 | PSMB8 (0.59) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL30429966 | 0.65 | — | — | |
| SCHEMBL18239092 | 0.63 | — | — | |
| SCHEMBL164767 | 0.62 | PSMB8 (0.38) | PSMB8 | |
| SCHEMBL17211305 | 0.61 | RAB9A (0.59) | PSMB8GSK3AGSK3B | |
| SCHEMBL12908842 | 0.61 | PSMB8 (0.44) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL18239093 | 0.61 | — | — | |
| SCHEMBL24256529 | 0.60 | PSMB8 (0.36) | PSMB8 | |
| SCHEMBL19190282 | 0.60 | PSMB8 (0.46) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL13058556 | 0.60 | HTT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |