Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24422532 | 0.77 | TLR8 (0.36) | — | |
| SCHEMBL24256526 | 0.72 | PSMB8 (0.46) | PSMB8 | |
| SCHEMBL24785611 | 0.67 | GRM6 (0.34) | — | |
| SCHEMBL4569220 | 0.66 | PI4KA (0.37) | — | |
| SCHEMBL26237386 | 0.65 | HSP90AA1 (0.30) | — | |
| SCHEMBL24256511 | 0.64 | PSMB8 (0.59) | PSMB8 | |
| SCHEMBL24322086 | 0.62 | ALDH1A1 (0.32) | — | |
| SCHEMBL24753227 | 0.61 | ALDH1A1 (0.36) | — | |
| SCHEMBL31032198 | 0.61 | ERBB2 (0.36) | — | |
| SCHEMBL28358688 | 0.61 | PIK3CG (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |