Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.59 |
| ▸ | GSK3A | P49840 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24256515 | 0.77 | PSMB8 (0.41) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL18368366 | 0.76 | RAB9A (0.40) | CDK1CCNB1FAAHCA1CA2 | |
| SCHEMBL19224384 | 0.76 | TLR8 (0.46) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL8040147 | 0.76 | PSMB8 (0.67) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL21063750 | 0.75 | PSMB8 (0.65) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL18905196 | 0.75 | SMN1; SMN2 (0.44) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL30938811 | 0.66 | PSMB8 (0.53) | PSMB8LMNACYP1A2CYP3A4HPGD | |
| SCHEMBL492446 | 0.66 | PSMB8 (0.53) | PSMB8LMNACYP1A2CYP3A4HPGD | |
| SCHEMBL26580900 | 0.65 | HPGD (0.33) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL17211305 | 0.65 | RAB9A (0.59) | PSMB8GSK3AGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |