Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MECP2 | P51608 | 1/20 | 0.58 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.58 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.58 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.58 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5126707 | 0.87 | NPY5R (0.69) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24257425 | 0.84 | MAPT (0.62) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24257641 | 0.84 | MAPT (0.62) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3915911 | 0.83 | MAPT (0.88) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 | |
| Bromide SCHEMBL6930883 | 0.82 | MAPT (0.86) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19782991 | 0.81 | MAPT (0.60) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1017669 | 0.79 | ALDH1A1 (0.67) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7678939 | 0.79 | MAPT (0.81) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL14276495 | 0.79 | NPY5R (1.00) | NPY5RCYP2D6 | |
| SCHEMBL24257655 | 0.78 | MAPT (0.57) | NPY5RMAPTSMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322815-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | UNIVERSITY OF HUDDERSFIELD (GB) | 2023-10-12 | — | — | US | disclosed |
| WO-2022034313-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | UNIVERSITY OF HUDDERSFIELD (GB) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322815-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | BRCA1, TPX2, XPA | NPY5R 1165/4885MAPT 4231/4885SMN1; SMN2 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.