Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | IRS1 | P35568 | 1/20 | 0.39 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257940 | 0.95 | AKT1 (0.42) | MEN1KMT2ASMN1; SMN2PKMAKT1 | |
| SCHEMBL24257854 | 0.95 | SMN1; SMN2 (0.41) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL24257935 | 0.95 | SMN1; SMN2 (0.40) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL24257934 | 0.93 | KDM4E (0.44) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL22080442 | 0.92 | SMN1; SMN2 (0.39) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL24257961 | 0.92 | SMN1; SMN2 (0.39) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL22079911 | 0.92 | ALDH1A1 (0.38) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL24257844 | 0.92 | HDAC3 (0.43) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL31682008 | 0.89 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2PKMTDP1 | |
| SCHEMBL22080214 | 0.88 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | NPC1 3240/4885MEN1 40/4885KMT2A 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.