Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SGMS1 | Q86VZ5 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257984 | 0.93 | CA2 (0.41) | KDM4ESMN1; SMN2PKMTDP1CA2 | |
| SCHEMBL24257905 | 0.93 | NPC1 (0.42) | SMN1; SMN2PKMTDP1CA2HTT | |
| SCHEMBL24257849 | 0.91 | HDAC3 (0.43) | KDM4ESMN1; SMN2PKMCA2ALDH1A1 | |
| SCHEMBL22080442 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2PKMTDP1CA2ALDH1A1 | |
| SCHEMBL24257961 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2PKMTDP1CA2ALDH1A1 | |
| SCHEMBL24257953 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2PKMTDP1CA2ALDH1A1 | |
| SCHEMBL24257940 | 0.88 | AKT1 (0.42) | KDM4ESMN1; SMN2PKMTDP1CA2 | |
| SCHEMBL24257854 | 0.88 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2PKMTDP1CA2 | |
| SCHEMBL24257935 | 0.87 | SMN1; SMN2 (0.40) | KDM4ESMN1; SMN2PKMTDP1CA2 | |
| SCHEMBL24257941 | 0.86 | TDP1 (0.54) | SMN1; SMN2PKMTDP1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | KDM4E 3938/4885SMN1; SMN2 1332/4885PKM 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.