Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22080205 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ACA2EPHX2NPC1 | |
| SCHEMBL26527725 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ACA2EPHX2MEN1 | |
| SCHEMBL31538106 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ACA2EPHX2MEN1 | |
| SCHEMBL24257984 | 0.78 | CA2 (0.41) | SMN1; SMN2KMT2ATDP1CA2MEN1 | |
| SCHEMBL24257941 | 0.78 | TDP1 (0.54) | SMN1; SMN2KMT2ATDP1CA2MEN1 | |
| SCHEMBL16330741 | 0.76 | GLP1R (0.43) | SMN1; SMN2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL2743010 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2ACA2MEN1CYP1A2 | |
| SCHEMBL24257967 | 0.73 | GLP1R (0.48) | SMN1; SMN2KMT2AEPHX2MEN1CYP1A2 | |
| SCHEMBL22080416 | 0.73 | GLP1R (0.43) | SMN1; SMN2KMT2ACA2EPHX2MEN1 | |
| SCHEMBL14845349 | 0.73 | CYP1A2 (0.42) | SMN1; SMN2KMT2ATDP1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | SMN1; SMN2 1332/4885KMT2A 953/4885TDP1 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.