Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257934 | 0.93 | KDM4E (0.44) | CA2KDM4ETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24257940 | 0.90 | AKT1 (0.42) | CA2KDM4ETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24257933 | 0.90 | CA2 (0.42) | CA2KDM4ESMN1; SMN2PKMKMT2A | |
| SCHEMBL24257941 | 0.89 | TDP1 (0.54) | CA2TDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL22029401 | 0.87 | NPC1 (0.40) | CA2TDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL22079946 | 0.87 | NPC1 (0.40) | CA2TDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL31682070 | 0.87 | NPC1 (0.40) | CA2TDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL24257988 | 0.87 | NPC1 (0.40) | CA2TDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL22080333 | 0.87 | NPC1 (0.40) | CA2TDP1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL24257935 | 0.87 | SMN1; SMN2 (0.40) | CA2KDM4ETDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | CA2 1521/4885KDM4E 3938/4885TDP1 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.