SCHEMBL24257979

SCHEMBL24257979

O=C(O)CCCCCCCCCCCCCc1ccc(Oc2ccc(S(=O)(=O)Nc3ncc(C(=O)NCCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)O)cn3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KMT2A Q03164 2/20 0.37
TDP1 Q9NUW8 3/20 0.37
PKM P14618 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
NR3C1 P04150 2/20 0.35
HDAC6 Q9UBN7 1/20 0.35
ITGB3 P05106 2/20 0.35
ITGA2B P08514 2/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22080331 0.98 TDP1 (0.38) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL22080450 0.94 ALDH1A1 (0.39) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL22029401 0.94 NPC1 (0.40) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL31682070 0.94 NPC1 (0.40) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL24257988 0.94 NPC1 (0.40) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL22080333 0.94 NPC1 (0.40) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL22079946 0.94 NPC1 (0.40) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL22079911 0.93 ALDH1A1 (0.38) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL24257961 0.92 SMN1; SMN2 (0.39) MEN1ALDH1A1KMT2ATDP1PKM
SCHEMBL22080442 0.92 SMN1; SMN2 (0.39) MEN1ALDH1A1KMT2ATDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893934-B1 INSULIN CONJUGATES SANOFI SA (FR) 2025-09-10 EP disclosed
US-20220048968-A1 INSULIN CONJUGATES SANOFI (FR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048968-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R MEN1 40/4885ALDH1A1 1829/4885KMT2A 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.