Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 9/20 | 0.32 |
| ▸ | JAK1 | P23458 | 8/20 | 0.32 |
| ▸ | JAK3 | P52333 | 7/20 | 0.32 |
| ▸ | CIT | O14578 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | MAP3K1 | Q13233 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258064 | 0.78 | ALDH1A1 (0.33) | L3MBTL1JAK2JAK1JAK3TYK2 | |
| SCHEMBL24258062 | 0.78 | ALDH1A1 (0.33) | L3MBTL1JAK2JAK1JAK3TYK2 | |
| SCHEMBL24258065 | 0.75 | JAK2 (0.56) | JAK2JAK1JAK3CITGAK | |
| SCHEMBL29837340 | 0.74 | JAK1 (0.61) | JAK2JAK1JAK3CITGAK | |
| SCHEMBL24258069 | 0.74 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL29837342 | 0.71 | JAK2 (0.46) | JAK2JAK1JAK3CITGAK | |
| SCHEMBL18195428 | 0.70 | L3MBTL1 (0.39) | L3MBTL1BRD4TSHRKIT | |
| SCHEMBL29837344 | 0.70 | JAK2 (0.40) | L3MBTL1JAK2JAK1JAK3TYK2 | |
| SCHEMBL4107778 | 0.70 | JAK1 (0.38) | L3MBTL1JAK2JAK1JAK3TYK2 | |
| SCHEMBL26541065 | 0.70 | JAK2 (0.40) | L3MBTL1JAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322787-A1 | PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED JAK INHIBITORS | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2023-10-12 | — | — | US | disclosed |
| WO-2022036030-A1 | PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED JAK INHIBITORS | CONCERT PHARMACEUTICALS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322787-A1 | PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED JAK INHIBITORS | JAK1, JAK3, JAK2 | L3MBTL1 4153/4885JAK2 3/4885JAK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.