SCHEMBL24258069

SCHEMBL24258069

BC1(B)C(/C(=C\C#N)n2cc(-c3ncnc4c3ccn4S(=O)(=O)c3ccc(C)cc3)cn2)C(B)(B)C(B)(B)C1(B)B

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24258064 0.86 ALDH1A1 (0.33) L3MBTL1
SCHEMBL24258062 0.86 ALDH1A1 (0.33) L3MBTL1
SCHEMBL24258068 0.74 L3MBTL1 (0.33) L3MBTL1
SCHEMBL29837340 0.69 JAK1 (0.61)
SCHEMBL24258065 0.69 JAK2 (0.56)
SCHEMBL26541065 0.67 JAK2 (0.40) L3MBTL1
SCHEMBL4107778 0.67 JAK1 (0.38) L3MBTL1
SCHEMBL29837344 0.67 JAK2 (0.40) L3MBTL1
SCHEMBL29837342 0.67 JAK2 (0.46)
SCHEMBL5405889 0.67 L3MBTL1 (0.52) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022036030-A1 PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED JAK INHIBITORS CONCERT PHARMACEUTICALS, INC. (US) 2022-02-17 WO disclosed