Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258176 | 0.93 | HTR6 (0.33) | HTR6 | |
| SCHEMBL21936943 | 0.83 | CD44 (0.30) | — | |
| SCHEMBL31304876 | 0.83 | CD44 (0.30) | — | |
| SCHEMBL21845453 | 0.78 | HTR2C (0.33) | — | |
| SCHEMBL15709840 | 0.78 | ADRA2A (0.33) | — | |
| SCHEMBL15709552 | 0.76 | — | — | |
| SCHEMBL24258222 | 0.76 | — | — | |
| SCHEMBL21750748 | 0.76 | HTR6 (0.32) | HTR6 | |
| SCHEMBL21845442 | 0.75 | LMNA (0.35) | — | |
| SCHEMBL30983155 | 0.75 | PARP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860714-B1 | 11,13-MODIFIED SAXITOXINS FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS INC (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022036297-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |