Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105478 | 0.82 | ALDH1A1 (0.53) | S1PR2S1PR1ANPEPERAP1ERAP2 | |
| SCHEMBL21823230 | 0.81 | EPHX1 (0.59) | ANPEPEPHX1 | |
| SCHEMBL8730913 | 0.79 | KMT2A (0.47) | ANPEPERAP1ERAP2ALDH1A1MEN1 | |
| SCHEMBL4895850 | 0.78 | EPHX1 (0.56) | S1PR2S1PR1ANPEPERAP1ERAP2 | |
| SCHEMBL45498 | 0.78 | S1PR2 (0.64) | S1PR2S1PR1ANPEPERAP1ERAP2 | |
| SCHEMBL19143555 | 0.78 | ANPEP (0.49) | ANPEPERAP1ERAP2ALDH1A1GRIK1 | |
| SCHEMBL2029005 | 0.78 | S1PR2 (0.64) | S1PR2S1PR1ANPEPERAP1ERAP2 | |
| SCHEMBL288680 | 0.78 | S1PR2 (0.64) | S1PR2S1PR1ANPEPERAP1ERAP2 | |
| Hydrochloric Acid SCHEMBL1927328 | 0.76 | S1PR2 (0.62) | S1PR2S1PR1ANPEPERAP1ERAP2 | |
| Acetic Acid SCHEMBL7374879 | 0.76 | DPP4 (0.47) | S1PR2S1PR1ANPEPERAP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177612-B1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION AS (DK) | 2022-02-23 | — | — | EP | disclosed |