SCHEMBL45498

SCHEMBL45498

NC(CCc1ccccc1)CC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 2/20 0.64
S1PR1 P21453 2/20 0.64
DPP4 P27487 2/20 0.55
ANPEP P15144 2/20 0.53
ERAP1 Q9NZ08 2/20 0.53
ERAP2 Q6P179 1/20 0.53
MMP12 P39900 2/20 0.53
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
MMP13 P45452 1/20 0.53
MMP14 P50281 1/20 0.53
KEAP1 Q14145 1/20 0.50
CPA1 P15085 2/20 0.47
CPB1 P15086 1/20 0.47
CPA3 P15088 1/20 0.47
CPB2 Q96IY4 1/20 0.47
HDAC3 O15379 1/20 0.47
MAPK1 P28482 1/20 0.47
ADRA1A P35348 1/20 0.47
HDAC4 P56524 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288680 1.00 S1PR2 (0.64) S1PR2S1PR1DPP4ANPEPERAP1
SCHEMBL2029005 1.00 S1PR2 (0.64) S1PR2S1PR1DPP4ANPEPERAP1
Hydrochloric Acid SCHEMBL1927328 0.98 S1PR2 (0.62) S1PR2S1PR1DPP4ANPEPERAP1
SCHEMBL27453353 0.89 S1PR2 (0.60) S1PR2S1PR1ANPEPERAP1ERAP2
SCHEMBL1669596 0.89 S1PR2 (0.60) S1PR2S1PR1ANPEPERAP1ERAP2
SCHEMBL6049800 0.87 S1PR2 (0.63) S1PR2S1PR1DPP4MMP12MMP2
SCHEMBL1105478 0.85 ALDH1A1 (0.53) S1PR2S1PR1DPP4ANPEPERAP1
SCHEMBL27999568 0.85 S1PR2 (0.65) S1PR2S1PR1DPP4ANPEPERAP1
SCHEMBL289093 0.85 S1PR2 (0.65) S1PR2S1PR1DPP4ANPEPERAP1
SCHEMBL6467442 0.84 S1PR2 (0.63) S1PR2S1PR1DPP4MMP12MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050100-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR AND SKIN CONDITIONS RELATED TO FOLLICULOPILOSEBACEOUS UNITS OLSEN ELISE A (US) 2025-03-06 WO claimed
US-20250049683-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH Olsen, Elise A. (US) 2025-02-13 US claimed
US-20210220248-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH OLSEN, Elise 2021-07-22 US claimed
US-20150258001-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH DUKE UNIVERSITY 2015-09-17 US claimed
US-20150257997-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH DUKE UNIVERSITY 2015-09-17 US claimed
CN-101525299-B Method for synthesizing beta-amino acid ASTATECH CHENGDU PHARMACEUTICAL CO LTD 2013-11-20 CN claimed
US-20120245205-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH OLSEN, ELISE A. 2012-09-27 US claimed
US-20120172318-A1 PEPTIDES AND PEPTIDOMIMETICS USEFUL FOR INHIBITING THE ACTIVITY OF PROSTAGLANDIN F2alpha RECEPTOR UNIVERSITE DE MONTREAL 2012-07-05 US claimed
EP-2459187-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH Duke University (US) 2012-06-06 EP claimed
EP-2289905-A1 Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2alpha receptor THERATECHNOLOGIES INC. (CA) 2011-03-02 EP claimed
WO-2011014649-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH DUKE UNIVERSITY (US) 2011-02-03 WO claimed
US-20060211626-A1 For treating preterm labor and dysmenorrhea THERATECHNOLOGIES, INC. (CA) 2006-09-21 US claimed
EP-1511764-A2 PEPTIDES AND PEPTIDOMIMETICS USEFUL FOR INHIBITING THE ACTIVITY OF PROSTAGLANDIN F sb 2a /sb RECEPTOR THERATECHNOLOGIES INC. (CA) 2005-03-09 EP claimed
WO-2003104266-A2 PEPTIDES AND PEPTIDOMIMETICS USEFUL FOR INHIBITING THE ACTIVITY OF PROSTAGLANDIN F2α RECEPTOR THERATECHNOLOGIES INC. (CA) 2003-12-18 WO claimed
US-12612605-B2 Carboxyesterase polypeptides for kinetic resolution CODEXIS, INC. (US) 2026-04-28 US disclosed
US-20260078417-A1 TRANSAMINASE BIOCATALYSTS CODEXIS, INC. (US) 2026-03-19 US disclosed
US-12565641-B2 Engineered terminal deoxynucleotidyl transferase variants CODEXIS, INC. (US) 2026-03-03 US disclosed
US-5220050-A PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS G. D. SEARLE & CO. (US) 1993-06-15 US disclosed
WO-1992020705-A1 PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1992-11-26 WO disclosed
EP-0513810-A1 Peptide mimetic compounds useful as platelet aggregation inhibitors G.D. Searle & Co. (US) 1992-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150257997-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR S1PR2 723/4885S1PR1 701/4885DPP4 4597/4885
US-20060211626-A1 For treating preterm labor and dysmenorrhea PGF, PTGFR, PTGER1 S1PR2 288/4885S1PR1 339/4885DPP4 4185/4885
US-12565641-B2 Engineered terminal deoxynucleotidyl transferase variants DNTT, RNGTT, POLM S1PR2 3986/4885S1PR1 4038/4885DPP4 684/4885
US-20150258001-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR S1PR2 723/4885S1PR1 701/4885DPP4 4597/4885
US-20210220248-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR S1PR2 723/4885S1PR1 701/4885DPP4 4597/4885
US-12612605-B2 Carboxyesterase polypeptides for kinetic resolution CES1, CPA1, RNGTT S1PR2 3349/4885S1PR1 3131/4885DPP4 327/4885
US-20260078417-A1 TRANSAMINASE BIOCATALYSTS XDH, AGXT, PEPD S1PR2 4876/4885S1PR1 4879/4885DPP4 145/4885
US-20250049683-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR S1PR2 723/4885S1PR1 701/4885DPP4 4597/4885
US-20120245205-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR S1PR2 723/4885S1PR1 701/4885DPP4 4597/4885
US-20120172318-A1 PEPTIDES AND PEPTIDOMIMETICS USEFUL FOR INHIBITING THE ACTIVITY OF PROSTAGLANDIN F2alpha RECEPTOR PGF, PTGFR, PTGDR2 S1PR2 289/4885S1PR1 334/4885DPP4 3756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.