Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19524948 | 0.86 | TDP1 (0.35) | — | |
| SCHEMBL337975 | 0.78 | EPHX2 (0.41) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL10248709 | 0.78 | ALDH1A1 (0.44) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL1924098 | 0.78 | EPHX2 (0.41) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL1923310 | 0.77 | — | — | |
| SCHEMBL338511 | 0.77 | — | — | |
| SCHEMBL1897777 | 0.77 | TDP1 (0.42) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL17294420 | 0.75 | — | — | |
| SCHEMBL4208454 | 0.73 | — | — | |
| SCHEMBL11683426 | 0.73 | ALOX5 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177612-B1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION AS (DK) | 2022-02-23 | — | — | EP | disclosed |