SCHEMBL2425837

SCHEMBL2425837

c1ccc(CNNc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.52
ALDH1A1 P00352 3/20 0.52
CTSD P07339 1/20 0.52
MAPT P10636 3/20 0.52
MAPK1 P28482 1/20 0.52
IDO1 P14902 2/20 0.48
THRB P10828 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP3A4 P08684 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MAOA P21397 2/20 0.45
MAOB P27338 1/20 0.45
KCNH3 Q9ULD8 1/20 0.44
HTT P42858 1/20 0.43
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH7 P40394 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28980137 0.85 MAPT (0.53) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL10643538 0.85 MEN1 (0.53) TDP1ALDH1A1CTSDMAPTMAPK1
Hydrochloric Acid SCHEMBL9471328 0.83 KCNH3 (0.54) ALDH1A1MAPTKMT2ACYP3A4KDM4E
SCHEMBL1792873 0.81 IDO1 (0.60) TDP1ALDH1A1MAPTIDO1THRB
SCHEMBL17087862 0.80 LTA4H (0.59) CYP3A4
SCHEMBL28636989 0.80 RAPGEF4 (0.46) MAPTMAPK1HPGD
SCHEMBL17454803 0.80 MAPT (0.53) TDP1ALDH1A1MAPTIDO1MEN1
SCHEMBL28636987 0.80 TP53 (0.45) TDP1ALDH1A1CTSDMAPTALOX12
Hydrochloric Acid SCHEMBL9737805 0.79 MAOB (0.55) ALDH1A1MAPTMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL7340226 0.78 MAPT (0.62) TDP1ALDH1A1MAPTIDO1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4971889-A Spectral sensitizing dye containnig a hydrazine residue FUJI PHOTO FILM CO., LTD. (JP) 1990-11-20 US claimed
CN-119194469-B Method for electrochemically synthesizing amine compound 山东金科力电源科技有限公司 2025-02-25 CN disclosed
CN-119194469-A Method for electrochemically synthesizing amine compound 山东金科力电源科技有限公司 2024-12-27 CN disclosed
CN-114690534-A Mask, photoetching device, mask manufacturing method and photoetching method based on mask 西湖大学 2022-07-01 CN disclosed
CN-114675507-A Lithographic apparatus and lithographic system 西湖大学 2022-06-28 CN disclosed
CN-107365306-B Heterocyclic compound and organic light-emitting device using the same LT素材株式会社 2020-09-01 CN disclosed
CN-111278880-A Active energy ray-curable resin composition and coating agent 三菱化学株式会社 2020-06-12 CN disclosed
WO-2016010402-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-01-21 WO disclosed
US-8324190-B2 Treatment of proliferative disorders with amino-substituted (E)-2,6- dialkoxystyryl 4-substituted benzylsulfones Temple University—Of the Commonwealth System of Higher Education (US) 2012-12-04 US disclosed
EP-1487428-B1 AMINO-SUBSTITUTED (E)-2,6-DIALKOXYSTYRYL 4-SUBSTITUTED BENZYLSULFONES FOR TREATING PROLIFERATIVE DISORDERS UNIV TEMPLE (US) 2011-09-21 EP disclosed
EP-0275667-A1 3-hetero-substituted-N-benzyl-indoles MERCK FROSST CANADA INC. (CA) 1988-07-27 EP disclosed
EP-0212635-A1 Water soluble triphenedioxazine compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed
EP-0187333-A2 Process for the production of polyurea and/or polyhydrazodicarbonamide dispersions and their further processing to polyurethanes. MILES INC. (US) 1986-07-16 EP disclosed
EP-0109931-A2 Process for the preparation of polyaryl amines showing methylene bridges ELPROCHINE AG (CH) 1984-05-30 EP disclosed
US-4294987-A ACID CATALYST THE UPJOHN COMPANY (US) 1981-10-13 US disclosed
US-4107102-A POLY(ALKYLENE ETHER)POLYOL, HYDRAZINE DERIVATIVE, DIISOCYANATE, BLOWING AGENT BAYER AKTIENGESELLSCHAFT (DE) 1978-08-15 US disclosed
US-4094970-A ELASTOMERIC POLYURETHANE-BASED ARTICLES HAVING AN INSECTICIDAL DEPOT GAS ACTION BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4089835-A Stable polyurethane dispersions and process for production thereof BAYER AKTIENGESELLSCHAFT (DT) 1978-05-16 US disclosed
US-4042537-A Process for the production of polyurethane foams BAYER AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-4041024-A FOR POLYAMIDES AND POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-09 US disclosed