Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657918 | 0.92 | CREBBP (0.42) | CREBBPBRD4 | |
| SCHEMBL19657389 | 0.80 | CREBBP (0.40) | CREBBPBRD4 | |
| SCHEMBL24258491 | 0.79 | CREBBP (0.62) | CREBBPBRD4 | |
| SCHEMBL24258507 | 0.76 | CREBBP (0.60) | CREBBPBRD4 | |
| SCHEMBL24258486 | 0.75 | CREBBP (0.61) | CREBBPBRD4 | |
| SCHEMBL21255156 | 0.71 | CREBBP (0.41) | CREBBPBRD4 | |
| SCHEMBL19657663 | 0.71 | CREBBP (0.43) | CREBBPBRD4 | |
| SCHEMBL24258509 | 0.70 | CREBBP (0.65) | CREBBPBRD4 | |
| SCHEMBL24258488 | 0.69 | CREBBP (0.67) | CREBBPBRD4 | |
| SCHEMBL19657640 | 0.66 | CREBBP (0.34) | CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464270-B1 | HETEROCYCLIC INHIBITORS OF CBP/EP300 AND THEIR USE IN THE TREATMENT OF CANCER | GENENTECH INC (US) | 2022-02-23 | — | — | EP | disclosed |