Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423988 | 0.85 | MAPT (0.36) | HRH3KCNH2RAB9AMAPTNPSR1 | |
| SCHEMBL219754 | 0.84 | PKM (0.51) | RAB9AMAPTNPSR1PKMKMT2A | |
| SCHEMBL2421851 | 0.84 | HRH3 (0.35) | HRH3KCNH2RAB9AMAPTPOLB | |
| SCHEMBL2429279 | 0.82 | HRH3 (0.33) | HRH3KCNH2RAB9AMAPTNPSR1 | |
| Cyclohexane SCHEMBL2428515 | 0.80 | HRH3 (0.40) | HRH3KCNH2RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL223636 | 0.79 | PKM (0.45) | RAB9AMAPTNPSR1PKMKMT2A | |
| SCHEMBL223649 | 0.78 | KCNH2 (0.46) | HRH3KCNH2RAB9AMAPTNPSR1 | |
| SCHEMBL223654 | 0.77 | KMT2A (0.46) | HRH3KCNH2RAB9AKMT2AALDH1A1 | |
| SCHEMBL2428638 | 0.77 | HRH3 (0.38) | HRH3KCNH2RAB9AMAPTPOLB | |
| SCHEMBL223823 | 0.77 | HRH3 (0.38) | HRH3KCNH2RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212283-B1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2011-09-21 | — | — | EP | claimed |