Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FHIT | P49789 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24444137 | 0.85 | POLB (0.42) | FHITPOLBENPP1P2RY1RNASEL | |
| SCHEMBL24258563 | 0.78 | FHIT (0.39) | FHITP2RY1RNASEL | |
| SCHEMBL21263871 | 0.73 | POLB (0.49) | FHITPOLBENPP1P2RY1RNASEL | |
| SCHEMBL24258614 | 0.72 | POLB (0.49) | FHITPOLBENPP1P2RY1RNASEL | |
| SCHEMBL24258639 | 0.72 | P2RY1 (0.43) | FHITP2RY1RNASEL | |
| SCHEMBL24258604 | 0.72 | POLB (0.41) | FHITPOLBENPP1P2RY1RNASEL | |
| SCHEMBL24504388 | 0.71 | RNASEL (0.42) | FHITPOLBENPP1P2RY1RNASEL | |
| SCHEMBL21263943 | 0.69 | FHIT (0.45) | FHITENPP1P2RY1 | |
| SCHEMBL2293016 | 0.69 | ATG7 (0.47) | POLBENPP1P2RY1 | |
| SCHEMBL2293022 | 0.69 | ATG7 (0.47) | POLBENPP1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752516-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-02-23 | — | — | EP | disclosed |