SCHEMBL2428112

SCHEMBL2428112

CCc1ccc2c(c1)[PH](=O)Oc1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
ALDH1A1 P00352 2/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
PDK2 Q15119 1/20 0.35
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33
POLB P06746 2/20 0.31
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431079 0.86 GPR3 (0.41) MAPTALDH1A1NPC1LMNAMAPK1
SCHEMBL2435389 0.85 SMN1; SMN2 (0.46) MAPTALDH1A1NPC1LMNAMAPK1
SCHEMBL2434113 0.84 ELANE (0.39) LMNAPDK2
SCHEMBL2438109 0.80 ELANE (0.42) LMNAPDK2
Alcohol SCHEMBL28762611 0.78 ALDH1A1 (0.30) ALDH1A1
SCHEMBL2431076 0.77 HDAC4 (0.35) MAPTALDH1A1NPC1LMNAMAPK1
SCHEMBL2434428 0.77 NPC1 (0.51) ALDH1A1NPC1LMNAMAPK1RAB9A
SCHEMBL29363087 0.76 HSP90AA1 (0.35) MAPK1TDP1
SCHEMBL30781 0.76 HSP90AA1 (0.35) MAPK1TDP1
SCHEMBL29395467 0.76 HSP90AA1 (0.35) MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed