SCHEMBL28498907

SCHEMBL28498907

COc1ccc2c(c1)[PH](=O)Oc1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.41
MAPT P10636 3/20 0.40
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
ALOX12 P18054 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAOB P27338 4/20 0.38
CYP19A1 P11511 4/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2A6 P11509 1/20 0.37
ACHE P22303 1/20 0.37
AR P10275 1/20 0.36
ABL1 P00519 1/20 0.36
ABCB1 P08183 1/20 0.36
BCR P11274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2438109 0.80 ELANE (0.42) KDM4EMAOBCYP19A1
SCHEMBL29363087 0.76 HSP90AA1 (0.35) KDM4ETDP1
SCHEMBL30781 0.76 HSP90AA1 (0.35) KDM4ETDP1
SCHEMBL29395467 0.76 HSP90AA1 (0.35) KDM4ETDP1
SCHEMBL2428112 0.76 MAPT (0.46) MAPTRAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL2425950 0.76 LMNA (0.36) MAPT
SCHEMBL28269644 0.75
SCHEMBL31183036 0.75 HSP90AA1 (0.34) KDM4ETDP1
Bromide SCHEMBL28619414 0.75 HSP90AA1 (0.34) KDM4ETDP1
SCHEMBL28437933 0.75 HSP90AA1 (0.34) KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112194682-A Novel photoinitiator and preparation method thereof 广州理文科技有限公司 2021-01-08 CN claimed
CN-112194682-A Novel photoinitiator and preparation method thereof 广州理文科技有限公司 2021-01-08 CN disclosed