Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL3108798 | 0.75 | SHBG (0.56) | SHBGEPHX1ALDH1A1TP53KDM4E | |
| SCHEMBL5400953 | 0.75 | SHBG (0.62) | SHBGEPHX1ALDH1A1TP53KDM4E | |
| SCHEMBL11903795 | 0.74 | SHBG (0.38) | SHBGEPHX1ALDH1A1 | |
| Methylamine SCHEMBL6014527 | 0.73 | SHBG (0.52) | SHBGEPHX1ALDH1A1TP53KDM4E | |
| SCHEMBL2342491 | 0.72 | SHBG (0.57) | SHBGEPHX1ALDH1A1TP53KDM4E | |
| SCHEMBL732223 | 0.72 | EPHX1 (0.34) | SHBGEPHX1TP53KDM4EGMNN | |
| SCHEMBL9974585 | 0.71 | CETP (0.33) | — | |
| SCHEMBL28340994 | 0.71 | ALDH1A1 (0.53) | SHBGEPHX1ALDH1A1TP53KDM4E | |
| SCHEMBL2996333 | 0.71 | SHBG (0.56) | SHBGEPHX1ALDH1A1TP53KDM4E | |
| SCHEMBL9563904 | 0.69 | SLC6A4 (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145984-B1 | THERAPEUTIC CONJUGATES WITH SULFATED DENDRIMERS FOR INTRACELLULAR TARGETING | ICD THERAPEUTICS GMBH (DE) | 2022-02-23 | — | — | EP | disclosed |