Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861074 | 0.84 | ALDH1A1 (0.45) | SLC6A4SLC6A3 | |
| SCHEMBL25135172 | 0.76 | — | — | |
| SCHEMBL8362551 | 0.75 | SLC6A4 (0.31) | SLC6A4SLC6A3 | |
| SCHEMBL28167562 | 0.74 | ALDH1A1 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL1276569 | 0.73 | SLC6A4 (0.31) | SLC6A4SLC6A3 | |
| SCHEMBL6855174 | 0.72 | — | — | |
| SCHEMBL8730256 | 0.71 | PTPN11 (0.33) | — | |
| SCHEMBL24259892 | 0.71 | SHBG (0.42) | — | |
| SCHEMBL24355585 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL20987599 | 0.71 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018201-A1 | New Process | F. HOFFMANN-LA ROCHE AG (CH) | 2013-01-17 | — | — | US | disclosed |
| US-20120157504-A1 | New Process | HOFFMANN-LA ROCHE INC. | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157504-A1 | New Process | CYP3A4, TPMT, CYP4B1 | CETP 313/4885SLC6A4 545/4885SLC6A3 608/4885 |
| US-20130018201-A1 | New Process | CYP4A11, UGT1A1, CYP11B1 | CETP 565/4885SLC6A4 3650/4885SLC6A3 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.