Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.42 |
| ▸ | CDK2 | P24941 | 5/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263128 | 0.89 | RAB9A (0.47) | LMNAPAK1SMYD3GAANAMPT | |
| SCHEMBL24263134 | 0.89 | SMYD3 (0.39) | HDAC8KMT2ASMYD3GAANAMPT | |
| SCHEMBL24263090 | 0.89 | NPC1 (0.47) | HDAC8KMT2APAK1SMYD3GAA | |
| SCHEMBL24263129 | 0.89 | HDAC8 (0.48) | HDAC8CCNA2CDK2CCNA1KMT2A | |
| SCHEMBL24263127 | 0.88 | MTNR1A (0.46) | HDAC8CCNA2CDK2CCNA1KMT2A | |
| SCHEMBL24263084 | 0.87 | KMT2A (0.42) | LMNAKMT2ASMYD3GAANAMPT | |
| SCHEMBL24263197 | 0.86 | TAOK1 (0.48) | LMNAKMT2ASMYD3GAA | |
| SCHEMBL24263089 | 0.86 | KDM5A (0.40) | HDAC8LMNAKMT2ASMYD3 | |
| SCHEMBL24263227 | 0.85 | HDAC8 (0.42) | HDAC8CCNA2CDK2CCNA1GAA | |
| SCHEMBL24263079 | 0.84 | TAOK1 (0.40) | HDAC8SMYD3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040508-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |