Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263134 | 0.85 | SMYD3 (0.39) | HDAC8NPC1RAB9ANAMPTSMN1; SMN2 | |
| SCHEMBL24263131 | 0.85 | HDAC8 (0.45) | HDAC8NAMPTGAACCNA2CDK2 | |
| SCHEMBL24263128 | 0.85 | RAB9A (0.47) | NPC1RAB9ANAMPTHPGDSMN1; SMN2 | |
| SCHEMBL24263129 | 0.85 | HDAC8 (0.48) | HDAC8NPC1RAB9ACCNA2CDK2 | |
| SCHEMBL24263090 | 0.85 | NPC1 (0.47) | HDAC8HDAC6NPC1RAB9ANAMPT | |
| SCHEMBL24263127 | 0.85 | MTNR1A (0.46) | HDAC8NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL24263084 | 0.83 | KMT2A (0.42) | HDAC1NPC1RAB9ANAMPTHPGD | |
| SCHEMBL24263197 | 0.82 | TAOK1 (0.48) | TAOK1GAAALDH1A1 | |
| SCHEMBL24263089 | 0.82 | KDM5A (0.40) | HDAC8NPC1RAB9ASMN1; SMN2TAOK1 | |
| SCHEMBL24263243 | 0.79 | GAA (0.43) | GAATSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040508-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |