Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MRE11 | P49959 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263503 | 0.78 | GSTO1 (0.47) | TYRMAPTNPC1RAB9APKM | |
| SCHEMBL26422946 | 0.72 | SMN1; SMN2 (0.37) | MAPTSMN1; SMN2HTTGAAMEN1 | |
| SCHEMBL3602268 | 0.66 | MAPT (0.56) | TYRMAPTNPC1RAB9AATP4A | |
| SCHEMBL17449667 | 0.65 | TYR (0.65) | TYRWNT3AMAPTRORCSMN1; SMN2 | |
| SCHEMBL21840600 | 0.65 | KMT2A (0.46) | TYRWNT3AMAPTNPC1RAB9A | |
| SCHEMBL18550658 | 0.64 | OPRM1 (0.60) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11484987 | 0.64 | TYR (0.61) | TYRNPC1RAB9AGAAABL1 | |
| SCHEMBL18560826 | 0.63 | TYR (0.65) | TYRMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12249170 | 0.63 | MAPT (0.58) | MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL18560827 | 0.63 | TYR (0.49) | TYRMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037927-A1 | NEW ISOBUTYRYAMIDE DERIVATIVES, COSMETIC AND/OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID COMPOUNDS, AND THEIR USE FOR THE PROPHYLAXIS AND TREATMENT OF SENSIBLE, IN PARTICULAR INFLAMED SKIN OR INFLAMMATORY SKIN CONDITIONS | BEIERSDORF AG (DE) | 2022-02-24 | — | — | WO | disclosed |