Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21185398 | 0.77 | TSHR (0.34) | SMN1; SMN2MEN1KMT2ACYP1A2GAA | |
| SCHEMBL18930369 | 0.77 | TRPA1 (0.43) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8767500 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2GPR174MEN1KMT2AEGFR | |
| SCHEMBL7903540 | 0.75 | ESR1 (0.52) | SMN1; SMN2GPR174MEN1KMT2AEGFR | |
| SCHEMBL8897839 | 0.73 | RAPGEF4 (0.47) | SMN1; SMN2GPR174EGFRCYP1A2GAA | |
| SCHEMBL11512360 | 0.72 | ALDH1A1 (0.54) | SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11419588 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2GPR174MEN1KMT2AEGFR | |
| SCHEMBL14415825 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2GPR174MEN1KMT2AEGFR | |
| SCHEMBL9979180 | 0.72 | NR1H4 (0.55) | SMN1; SMN2GPR174MEN1KMT2AEGFR | |
| SCHEMBL24263193 | 0.72 | TYR (0.46) | SMN1; SMN2MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | SMN1; SMN2 1694/4885GPR174 2102/4885MEN1 2845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.