Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263104 | 0.86 | MTNR1A (0.50) | GAAKDM5AMTNR1AMTNR1BCA1 | |
| SCHEMBL24263216 | 0.82 | MTNR1A (0.44) | GAAKDM5AMTNR1AMTNR1BCA1 | |
| SCHEMBL24263107 | 0.82 | MTNR1A (0.53) | GAAKDM5AMTNR1AMTNR1BCA1 | |
| SCHEMBL24263240 | 0.82 | GAA (0.43) | GAAKDM5AMTNR1AMTNR1B | |
| SCHEMBL24263084 | 0.82 | KMT2A (0.42) | GAAMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL24263080 | 0.81 | MTNR1A (0.55) | GAAKDM5AMTNR1AMTNR1BCA1 | |
| SCHEMBL24263243 | 0.79 | GAA (0.43) | GAAKDM5AMTNR1AMTNR1BCCR2 | |
| SCHEMBL24263128 | 0.79 | RAB9A (0.47) | GAAMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL24263105 | 0.79 | MTNR1A (0.47) | GAAMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL24263127 | 0.78 | MTNR1A (0.46) | GAAKDM5AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040508-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |