Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 4/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | TYK2 | P29597 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263240 | 0.94 | GAA (0.43) | GAAJAK1JAK2TYK2JAK3 | |
| SCHEMBL24263104 | 0.82 | MTNR1A (0.50) | GAACA12CA1CA2CA7 | |
| SCHEMBL24263107 | 0.79 | MTNR1A (0.53) | GAACA12CA1CA2CA7 | |
| SCHEMBL24263216 | 0.79 | MTNR1A (0.44) | GAACA1CA2KDM5AMTNR1A | |
| SCHEMBL24263236 | 0.79 | GAA (0.41) | GAACA1CA2KDM5ALMNA | |
| SCHEMBL24263227 | 0.79 | HDAC8 (0.42) | GAAALDH1A1TSHRTP53 | |
| SCHEMBL24263080 | 0.77 | MTNR1A (0.55) | GAACA12CA1CA2CA7 | |
| SCHEMBL24263127 | 0.77 | MTNR1A (0.46) | GAAKDM5AMTNR1AMTNR1B | |
| SCHEMBL24263245 | 0.76 | ALDH1A1 (0.42) | GAACA12CA1CA2CA7 | |
| SCHEMBL24263321 | 0.74 | GAA (0.46) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040508-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |