Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263406 | 0.82 | TYK2 (0.69) | TYK2PDE4DJAK2JAK1JAK3 | |
| SCHEMBL22421800 | 0.82 | TYK2 (0.68) | TYK2PDE4DJAK2JAK1JAK3 | |
| SCHEMBL22272929 | 0.81 | TYK2 (0.62) | TYK2PDE4D | |
| SCHEMBL24263266 | 0.80 | TYK2 (0.63) | TYK2PDE4D | |
| SCHEMBL24263261 | 0.79 | TYK2 (0.57) | TYK2PDE4D | |
| SCHEMBL21571860 | 0.78 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL21571871 | 0.77 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL24263296 | 0.76 | TYK2 (0.78) | TYK2PDE4D | |
| SCHEMBL29754460 | 0.76 | TYK2 (0.78) | TYK2PDE4D | |
| SCHEMBL31218807 | 0.76 | TYK2 (0.74) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |