Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263264 | 0.81 | TYK2 (0.64) | TYK2PDE4D | |
| SCHEMBL24263406 | 0.80 | TYK2 (0.69) | TYK2PDE4D | |
| SCHEMBL22421800 | 0.80 | TYK2 (0.68) | TYK2PDE4D | |
| SCHEMBL22272927 | 0.79 | TYK2 (0.43) | TYK2PDE4D | |
| SCHEMBL24263266 | 0.78 | TYK2 (0.63) | TYK2PDE4D | |
| SCHEMBL21571871 | 0.77 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL21571860 | 0.76 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL24263296 | 0.76 | TYK2 (0.78) | TYK2PDE4D | |
| SCHEMBL29754460 | 0.76 | TYK2 (0.78) | TYK2PDE4D | |
| SCHEMBL31218703 | 0.76 | TYK2 (0.70) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154474-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-07-30 | — | — | WO | disclosed |