Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.47 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263494 | 0.92 | TYK2 (0.56) | TYK2STAT3 | |
| SCHEMBL24263399 | 0.87 | TYK2 (0.47) | TYK2STAT3 | |
| SCHEMBL24263490 | 0.85 | TYK2 (0.43) | TYK2STAT3HPGDS | |
| SCHEMBL24263384 | 0.84 | TYK2 (0.64) | TYK2 | |
| SCHEMBL24263411 | 0.84 | TYK2 (0.57) | TYK2STAT3 | |
| SCHEMBL24263278 | 0.83 | TYK2 (0.56) | TYK2STAT3 | |
| SCHEMBL24263415 | 0.82 | TYK2 (0.40) | TYK2STAT3HPGDS | |
| SCHEMBL24263262 | 0.81 | TYK2 (0.40) | TYK2STAT3HPGDS | |
| SCHEMBL24263496 | 0.79 | HPGDS (0.46) | TYK2STAT3HPGDS | |
| SCHEMBL24263263 | 0.79 | HPGDS (0.46) | TYK2STAT3HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |