SCHEMBL2426428

SCHEMBL2426428

CCCCCNN1CCOC(CCC)C1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
EPHX1 P07099 1/20 0.40
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14633745 0.73 LMNA (0.37)
SCHEMBL6232904 0.72 PDK1 (0.34)
SCHEMBL2198192 0.72 LMNA (0.33)
SCHEMBL28245251 0.71 GNAI3 (0.59) GNAI3GNAO1GNAI1EPHX1ALDH1A1
Iodide SCHEMBL28247311 0.69 GNAI3 (0.58) GNAI3GNAO1GNAI1EPHX1ALDH1A1
Hydrochloric Acid SCHEMBL28185748 0.69 GNAI3 (0.62) GNAI3GNAO1GNAI1EPHX1ALDH1A1
Bromide SCHEMBL28507361 0.69 GNAI3 (0.58) GNAI3GNAO1GNAI1EPHX1ALDH1A1
Bromide SCHEMBL28185707 0.69 GNAI3 (0.58) GNAI3GNAO1GNAI1EPHX1ALDH1A1
SCHEMBL27876653 0.69 GNAI3 (0.58) GNAI3GNAO1GNAI1EPHX1ALDH1A1
Bromide SCHEMBL28247315 0.69 GNAI3 (0.58) GNAI3GNAO1GNAI1EPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1889606-B2 Dyeing composition for keratinous fibres comprising an anionic associative polymer and a polymer with acrylamide, dialkyldiallylammonium halide and vinyl carboxylic acid patterns L'ORÉAL (FR) 2017-08-23 EP disclosed
EP-1341504-B2 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING AN ASSOCIATIVE POLYMER AND A PEARLING AGENT ORÉAL L (FR) 2016-04-20 EP disclosed
WO-2013125053-A1 PROCESS FOR TREATING KERATIN FIBERS L'OREAL (FR) 2013-08-29 WO disclosed
US-8025701-B2 Use of natural dyes for coloring human hair L'OREAL S.A. (FR) 2011-09-27 US disclosed
US-20100306929-A1 USE OF NATURAL DYES FOR COLORING HUMAN HAIR L'OREAL S.A. (FR) 2010-12-09 US disclosed
EP-1428510-A1 Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use L'OREAL (FR) 2004-06-16 EP disclosed
EP-0858795-A1 Use of polymers having a critical temperature of the LCST or UCST-type in and for the preparation of dermo-cosmetic compositions, and compositions containing these L'OREAL (FR) 1998-08-19 EP disclosed