SCHEMBL2426464

SCHEMBL2426464

COc1c(N)ccc(-c2ccc(N)c(OC)c2Cl)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
NPC1 O15118 2/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
APEX1 P27695 1/20 0.39
RECQL P46063 1/20 0.39
RAB9A P51151 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
MCL1 Q07820 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTR1A P08908 1/20 0.37
HTR1D P28221 1/20 0.37
HTR2C P28335 1/20 0.37
HTR7 P34969 1/20 0.37
HTR5A P47898 1/20 0.37
ALOX5AP P20292 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10944142 0.82 TUBB4A (0.42) ALDH1A1TDP1NPC1MEN1MAPT
SCHEMBL30126262 0.82 TUBB4A (0.42) ALDH1A1TDP1NPC1MEN1MAPT
SCHEMBL24824751 0.80 CYP3A4 (0.40) ALDH1A1TDP1NPC1POLBHTR1A
SCHEMBL5238486 0.80 IDO1 (0.45) ALDH1A1TDP1NPC1MEN1MAPT
SCHEMBL30407777 0.78 ALOX5AP (0.38) ALDH1A1TDP1NPC1MEN1POLB
SCHEMBL22366678 0.78 HTR2C (0.37) ALDH1A1TDP1NPC1HTR1AHTR1D
SCHEMBL29398904 0.78 HTR2C (0.37) ALDH1A1TDP1NPC1HTR1AHTR1D
SCHEMBL3837168 0.78 ALDH1A1 (0.33) ALDH1A1TDP1NPC1HTR1AHTR1D
SCHEMBL3788843 0.78 ALDH1A1 (0.39) ALDH1A1TDP1MEN1POLBMAPT
SCHEMBL28366576 0.77 ALDH1A1 (0.46) ALDH1A1TDP1MEN1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8026036-B2 Photosensitive resin composition and circuit substrate employing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-09-27 US disclosed
US-20090202786-A1 Photosensitive Resin Composition and Circuit Substrate Employing the Same NIPPON STEEL CHEMICALS CO., LTD (JP) 2009-08-13 US disclosed
EP-0055218-B1 MANUFACTURE OF AZOIC COMPOUNDS CIBA-GEIGY AG (CH) 1986-03-26 EP disclosed
US-4496481-A REACTING AMINE, COUPLING COMPONENT AND NITRITE;PIGMENTS AND DISPERSE DYES CIBA-GEIGY CORPORATION (US) 1985-01-29 US disclosed
EP-0055218-A2 Manufacture of azoic compounds CIBA-GEIGY AG (CH) 1982-06-30 EP disclosed