Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113551 | 0.83 | HPGD (0.69) | HPGDPDE4ALMNA | |
| SCHEMBL28522649 | 0.81 | CXCR1 (0.50) | HPGDCHRM1PDE4APTGS1PTGS2 | |
| SCHEMBL8127958 | 0.81 | TRPV1 (0.62) | HPGDLMNA | |
| SCHEMBL826024 | 0.81 | HPGD (0.51) | HPGDLMNACYP2C9 | |
| SCHEMBL2451676 | 0.79 | ESRRB (0.55) | HPGDLMNA | |
| SCHEMBL31344791 | 0.79 | HPGD (0.50) | HPGDLMNA | |
| SCHEMBL13255794 | 0.79 | HPGD (0.69) | HPGDLMNA | |
| SCHEMBL24474317 | 0.79 | HPGD (0.50) | HPGDLMNA | |
| SCHEMBL8246709 | 0.79 | ACACB (0.59) | HPGDCHRM1PDE4APTGS1PTGS2 | |
| SCHEMBL4388479 | 0.78 | ALDH1A1 (0.65) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040173-A1 | TRANSGLUTAMINASE-MEDIATED CONJUGATION | Tallac Therapeutics, Inc. (US) | 2022-02-24 | — | — | WO | disclosed |
| CN-112299938-B | Method for preparing amine compound by reducing amide compound | 中国科学院兰州化学物理研究所 | 2021-12-28 | — | — | CN | disclosed |
| CN-112299938-A | Method for preparing amine compound by reducing amide compound | 中国科学院兰州化学物理研究所 | 2021-02-02 | — | — | CN | disclosed |