SCHEMBL28522649

SCHEMBL28522649

CNC(=O)Cc1ccc(CC(C)C)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR1 P25024 5/20 0.50
CXCR2 P25025 5/20 0.50
PTGS1 P23219 4/20 0.50
PTGS2 P35354 4/20 0.50
LMNA P02545 3/20 0.50
CYP2C9 P11712 2/20 0.50
AKR1C3 P42330 2/20 0.50
ALOX5 P09917 2/20 0.50
ALB P02768 1/20 0.50
ESR1 P03372 1/20 0.50
RARB P10826 1/20 0.50
ADRB3 P13945 1/20 0.50
NFKB1 P19838 1/20 0.50
HTR2A P28223 1/20 0.50
NR1I3 Q14994 1/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
CXCL8 P10145 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
AKR1C2 P52895 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24500947 0.82 SLC7A5 (0.46)
SCHEMBL8008897 0.81 ALDH1A1 (0.47) CXCR1CXCR2PTGS1PTGS2LMNA
SCHEMBL24264697 0.81 HPGD (0.56) CXCR1CXCR2PTGS1PTGS2LMNA
SCHEMBL13329804 0.81 CNR2 (0.58) LMNAHPGD
SCHEMBL8128592 0.80 CA1 (0.53) CXCR1CXCR2PTGS1PTGS2LMNA
SCHEMBL27059184 0.80 HPGD (0.46) CXCR1CXCR2PTGS1PTGS2LMNA
Ibufenac SCHEMBL24244 0.78 PTGS1 (0.60) CXCR1CXCR2PTGS1PTGS2LMNA
SCHEMBL241137 0.78 POLB (0.58) CXCR1CXCR2PTGS1PTGS2LMNA
SCHEMBL11800587 0.78 PTGS1 (0.55) CXCR1CXCR2PTGS1PTGS2LMNA
SCHEMBL171860 0.78 HPGD (0.59) LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108341733-B Novel electronic salt system and reduction method of unsaturated hydrocarbon compound 中国农业大学 2021-01-08 CN disclosed