Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.55 |
| ▸ | ESRRG | P62508 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24272325 | 0.88 | BCHE (0.52) | ESRRBESRRGLMNARAB9AKDM4E | |
| SCHEMBL826024 | 0.86 | HPGD (0.51) | LMNAHPGDNPC1RAB9AKDM4E | |
| SCHEMBL9327260 | 0.85 | ESRRB (0.60) | ESRRBESRRGLMNACA2CAMK2A | |
| SCHEMBL31344791 | 0.84 | HPGD (0.50) | LMNAHPGDNPC1RAB9AKDM4E | |
| SCHEMBL13255794 | 0.84 | HPGD (0.69) | LMNAHPGDNPC1RAB9A | |
| SCHEMBL24474317 | 0.84 | HPGD (0.50) | LMNAHPGDNPC1RAB9AKDM4E | |
| SCHEMBL13933261 | 0.83 | HTT (0.51) | LMNACA2HPGDNPC1RAB9A | |
| SCHEMBL780470 | 0.82 | HPGD (0.49) | LMNAHPGDNPC1RAB9AKDM4E | |
| SCHEMBL21185332 | 0.82 | HPGD (0.49) | LMNAHPGDNPC1RAB9AKDM4E | |
| SCHEMBL4388479 | 0.82 | ALDH1A1 (0.65) | LMNACA2TRPV1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160266133-A1 | NUCLEIC ACID-SCAFFOLDED SMALL MOLECULE LIBRARIES | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| US-8013153-B2 | Substituted pyrimidine kinase inhibitors | JANSSEN PHARMACEUTICA, N.V. (BE) | 2011-09-06 | — | — | US | disclosed |
| US-20070254896-A1 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-11-01 | — | — | US | disclosed |
| WO-2007109783-A2 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160266133-A1 | NUCLEIC ACID-SCAFFOLDED SMALL MOLECULE LIBRARIES | SNRPE, SARNP, SARS1 | ESRRB 2515/4885ESRRG 2971/4885LMNA 444/4885 |
| US-20070254896-A1 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | DTYMK, TK1, DCK | ESRRB 3809/4885ESRRG 4002/4885LMNA 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.