SCHEMBL24264754

SCHEMBL24264754

O=C(O)CCCc1cc(F)c(C(F)(F)F)c(F)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.47
MAPK1 P28482 1/20 0.47
ADRA1A P35348 1/20 0.47
HDAC4 P56524 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HDAC1 Q13547 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
DAO P14920 1/20 0.44
CYP1A2 P05177 2/20 0.42
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL584537 0.89 DAO (0.46) DAOFFAR1FFAR4RXRARXRB
SCHEMBL24264807 0.82 SMN1; SMN2 (0.53) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL24264909 0.79 CYP1A2 (0.50) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL30428260 0.79 CYP1A2 (0.50) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL26759286 0.79 HDAC1 (0.50) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL7812479 0.79 LMNA (0.51) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL29009790 0.78 RXRA (0.50) SMN1; SMN2DAOHSD17B10MAPTRXRA
SCHEMBL29009820 0.77 FFAR4 (0.53) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL30427041 0.77 FFAR4 (0.53) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL30427994 0.77 MAPT (0.53) HDAC3MAPK1ADRA1AHDAC4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-B Small molecule albumin binding agents 俄勒冈健康科学大学 2025-05-23 CN disclosed
WO-2024080333-A1 METHOD FOR PRODUCING N-SUBSTITUTED AMINO ACID RESIDUE-CONTAINING CYCLIC PEPTIDE COMPOUND 中外製薬株式会社 2024-04-18 WO disclosed
US-20230348378-A1 SMALL MOLECULE ALBUMIN BINDERS OREGON HEALTH & SCIENCE UNIVERSITY 2023-11-02 US disclosed
US-20230348378-A1 SMALL MOLECULE ALBUMIN BINDERS OREGON HEALTH & SCIENCE UNIVERSITY 2023-11-02 US disclosed
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed
WO-2022040607-A1 SMALL MOLECULE ALBUMIN BINDERS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2022-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348378-A1 SMALL MOLECULE ALBUMIN BINDERS ALB, FABP1, FABP3 HDAC3 3478/4885MAPK1 3582/4885ADRA1A 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.