SCHEMBL29009790

SCHEMBL29009790

O=C(O)Cc1cc(F)c(C(F)(F)F)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 12/20 0.50
RXRG P48443 12/20 0.50
RXRB P28702 11/20 0.50
PSEN1 P49768 1/20 0.42
PSEN2 P49810 1/20 0.42
APH1B Q8WW43 1/20 0.42
NCSTN Q92542 1/20 0.42
APH1A Q96BI3 1/20 0.42
PSENEN Q9NZ42 1/20 0.42
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
DAO P14920 1/20 0.41
AKR1B1 P15121 1/20 0.40
KDM4E B2RXH2 1/20 0.38
RGS12 O14924 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29009898 0.88 RXRA (0.44) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL30427820 0.88 RXRA (0.44) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL30427747 0.88 RXRA (0.44) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL29009852 0.88 RXRA (0.44) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL584537 0.81 DAO (0.46) RXRARXRGRXRBDAO
SCHEMBL908287 0.79 CES2 (0.46) TSHRAKR1B1KDM4ERGS12LMNA
SCHEMBL24264754 0.78 HDAC3 (0.47) RXRARXRGRXRBSMN1; SMN2DAO
SCHEMBL299357 0.77 GAA (0.47) RXRARXRGRXRBTSHRAKR1B1
SCHEMBL30428478 0.76 RXRA (0.45) RXRARXRGRXRBTSHRSMN1; SMN2
SCHEMBL29009786 0.76 RXRA (0.45) RXRARXRGRXRBTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-B Small molecule albumin binding agents 俄勒冈健康科学大学 2025-05-23 CN disclosed
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed