Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20445444 | 0.97 | POLB (0.38) | POLBHTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL19543390 | 0.89 | CSNK2A1 (0.37) | ALDH1A1SMN1; SMN2CSNK2A1 | |
| SCHEMBL24703987 | 0.79 | PTGS2 (0.44) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL27867050 | 0.72 | ALDH1A1 (0.42) | POLBALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11319308 | 0.72 | CALM1 (0.46) | POLBHTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17149189 | 0.71 | PPARG (0.34) | CSNK2A1 | |
| SCHEMBL24265126 | 0.69 | CSNK2A1 (0.47) | CSNK2A1 | |
| SCHEMBL24377558 | 0.69 | KDM4E (0.37) | POLBALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL18389553 | 0.69 | MEN1 (0.55) | HTTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23077907 | 0.69 | MEN1 (0.44) | POLBHTTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220054645-A1 | Targeted Delivery of Therapeutic Molecules | Zhang, Peter (CN) | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220054645-A1 | Targeted Delivery of Therapeutic Molecules | CD44, CD47, EPCAM | POLB 4291/4885HTT 364/4885ALDH1A1 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.