Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5178154 | 0.79 | GNAI3 (0.43) | ITGB3ITGA2BHTR6HTR1ADRD2 | |
| SCHEMBL2426719 | 0.78 | KDM4E (0.43) | DCUN1D1UBE2MMLNR | |
| SCHEMBL17072657 | 0.77 | SMN1; SMN2 (0.47) | PTPN1HTR6HTR1ADRD2HTR2A | |
| Trifluoroacetic Acid SCHEMBL2422738 | 0.77 | HRH1 (0.57) | — | |
| Trifluoroacetic Acid SCHEMBL4691138 | 0.74 | CACNA1B (0.54) | CACNA1BHRH4HRH3HTR6SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4690307 | 0.74 | CACNA1B (0.54) | CACNA1BHRH4HRH3HTR6SMN1; SMN2 | |
| SCHEMBL8548152 | 0.73 | HTR6 (0.47) | PTPN1HTR6HTR1ADRD2HTR2A | |
| Trifluoroacetic Acid SCHEMBL6396756 | 0.73 | CACNA1B (0.48) | CACNA1BHRH4HRH3HTR6SMN1; SMN2 | |
| SCHEMBL30444517 | 0.71 | GRIK1 (0.54) | PTPN1HTR6HTR1ADRD2HTR2A | |
| Trifluoroacetic Acid SCHEMBL5036144 | 0.71 | CARM1 (0.47) | DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012995-B1 | Pharmaceutically active sulfonamide derivatives | MERCK SERONO SA (CH) | 2011-09-06 | — | — | US | disclosed |
| EP-1218374-B1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2005-11-16 | — | — | EP | disclosed |
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |