Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267168 | 0.91 | ALDH1A1 (0.32) | MTNR1AMTNR1B | |
| SCHEMBL23418849 | 0.80 | TSHR (0.36) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL24267250 | 0.76 | — | — | |
| SCHEMBL23023352 | 0.73 | CHRM3 (0.47) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL24199796 | 0.71 | RORC (0.32) | MTNR1AMTNR1B | |
| SCHEMBL14527664 | 0.71 | ALDH1A1 (0.35) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL19173928 | 0.71 | CES2 (0.38) | MTNR1AMTNR1B | |
| SCHEMBL24267218 | 0.68 | NR1H2 (0.34) | — | |
| SCHEMBL20803956 | 0.67 | — | — | |
| SCHEMBL31173354 | 0.65 | PLAU (0.43) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |