Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344671 | 0.90 | TSHR (0.34) | TSHRGNAO1 | |
| SCHEMBL24480580 | 0.88 | GNAO1 (0.34) | GBA1GNAO1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL24481344 | 0.88 | GBA1 (0.37) | GBA1TSHRGNAO1CACNA2D1CACNA1B | |
| SCHEMBL24940877 | 0.88 | CHRM5 (0.39) | CHRM5ADRA2CACHEOPRM1OPRL1 | |
| SCHEMBL24267132 | 0.87 | GBA1 (0.36) | GBA1TSHRGNAO1CACNA2D1CACNA1B | |
| SCHEMBL24267397 | 0.85 | GBA1 (0.36) | GBA1TSHRGNAO1CACNA2D1CACNA1B | |
| SCHEMBL22565121 | 0.84 | NCF1 (0.41) | CACNA2D1CACNA1BCACNB1CHRM5ADRA2C | |
| SCHEMBL20317409 | 0.83 | CHRM5 (0.34) | GBA1TSHRGNAO1CACNA2D1CACNA1B | |
| SCHEMBL30121551 | 0.81 | GBA1 (0.39) | GBA1TSHRGNAO1CACNA2D1CACNA1B | |
| SCHEMBL24717358 | 0.80 | CYP2D6 (0.36) | GBA1TSHRALDH1A1CYP2C19KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023016518-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2023-02-16 | — | — | WO | disclosed |
| WO-2023009701-A1 | — | — | 2023-02-02 | — | — | WO | disclosed |
| WO-2023283263-A1 | CITRATE SALT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | FOGHORN THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |