Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | SDCBP | O00560 | 1/20 | 0.31 |
| ▸ | SDC2 | P34741 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22300324 | 0.84 | MAPT (0.34) | MAPTMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL20327290 | 0.78 | ALDH1A1 (0.35) | MAPTMEN1KMT2ADDB1CRBN | |
| SCHEMBL19310141 | 0.77 | HIF1A (0.37) | MAPTMEN1KMT2ADDB1CRBN | |
| SCHEMBL27404404 | 0.77 | DDB1 (0.36) | MEN1KMT2ADDB1CRBNIKZF3 | |
| SCHEMBL20291143 | 0.75 | HDAC1 (0.41) | HDAC6 | |
| SCHEMBL24290290 | 0.75 | MAPK8 (0.32) | MAPTCRBNALDH1A1POLBL3MBTL1 | |
| SCHEMBL24289130 | 0.75 | BRD4 (0.35) | MAPTMEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL17724330 | 0.75 | TYMS (0.40) | MAPTMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL21924027 | 0.74 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL24291561 | 0.74 | PTPN11 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022042707-A1 | CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN (CBP) AND/OR ADENOVIRAL E1A BINDING PROTEIN OF 300 KDA (P300) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI) , INC. (CN) | 2022-03-03 | — | — | WO | disclosed |