Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24291561 | 0.83 | PTPN11 (0.34) | SYKMAPK1 | |
| SCHEMBL22300324 | 0.78 | MAPT (0.34) | MAPTPARP1MEN1KMT2AALOX15 | |
| SCHEMBL24291623 | 0.77 | PIM1 (0.37) | BRD4MAPK1PARP1KMT2A | |
| SCHEMBL20327290 | 0.76 | ALDH1A1 (0.35) | BRD4MAPTPARP1MEN1KMT2A | |
| SCHEMBL20291143 | 0.76 | HDAC1 (0.41) | — | |
| SCHEMBL22512205 | 0.76 | UTS2R (0.40) | — | |
| SCHEMBL24269089 | 0.75 | RXRA (0.34) | MAPTMEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL22511600 | 0.72 | UTS2R (0.32) | MAPTALOX15SMN1; SMN2 | |
| SCHEMBL24937929 | 0.72 | HDAC1 (0.37) | — | |
| SCHEMBL24290290 | 0.72 | MAPK8 (0.32) | BRD4AURKBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |