Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | SDCBP | O00560 | 1/20 | 0.31 |
| ▸ | SDC2 | P34741 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24269089 | 0.84 | RXRA (0.34) | MAPTMEN1KMT2AALOX15POLB | |
| SCHEMBL20327290 | 0.82 | ALDH1A1 (0.35) | MAPTMEN1KMT2AALOX15POLB | |
| SCHEMBL20291143 | 0.79 | HDAC1 (0.41) | — | |
| SCHEMBL24289130 | 0.78 | BRD4 (0.35) | MAPTMEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL24291561 | 0.78 | PTPN11 (0.34) | — | |
| SCHEMBL24290290 | 0.77 | MAPK8 (0.32) | MAPTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7677830 | 0.77 | KDM4E (0.41) | MAPTMEN1KMT2AALOX15POLB | |
| SCHEMBL24937929 | 0.76 | HDAC1 (0.37) | — | |
| SCHEMBL22511600 | 0.76 | UTS2R (0.32) | MAPTALOX15POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL25654057 | 0.76 | ALOX15 (0.31) | MAPTALOX15POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156017-A1 | TARGETED UBIQUITINATION DEGRADATION BRD4 PROTEIN COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2020-08-06 | — | — | WO | disclosed |